It seems clear that Karolina has feelings for Nico.
VIRGINIA GARDNER: She kind of realizes what her real desires are, one of them being, as we find out later on in the season—
LYRICA OKANO: Me.
GARDNER: Nico. So fans will be very happy to see that this happens.

So the show will be exploring a potential romance?
GARDNER: Oh, it’s happening. There’s definitely some love triangles, but it’s happening.
[...]
GARDNER: I think fans will be really excited.
OKANO: We were very, very excited.
GARDNER: We were excited because we read the comics, and we’re like, “God, I really hope that they happen,” and we’re happy.
OKANO: We’ve been pushing for this.