I think it goes without saying that the Lannister clan is forever doomed when she goes, and it's partly Tybalt's own doing which is part of his own tragedy. Baby Damon turns into a drunk. The twins are psychotic and die. Krea is psychotic and probably dies. Kenric is the last hope.
And Tybalt's betrayal will be his own undoing in the end too.
YOU SHOULD ABSOLUTELY MAKE TYBALT'S MUM I SUPPORT THIS ONE HUNDRED PERCENT. DO EET.