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Hugh Laurie & Lisa Edelstein (House & Cuddy in House)
George Clooney & Julianna Margulies (Doug & Carol in ER)
Anthony Edwards & Sherry Stringfield (Mark & Susan in ER)
Leonardo Dicaprio & Kate winset (Jack & Rose in Titanic)
Patrick Dempsey & Kate Walsh (Derek & Addison in Greys Anatomy)
Courtney Cox & Matthew Perry (Monica & Chandler in Friends)
Kira Knighty & Johnny Depp (Elizabeth & Jack in POTC)
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