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I could see Nina and Jake potentially having an argument over mandates, with Nina not wanting to risk people's health in the restaurant.
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I remember when Jake was rather careless (if I remember correctly) over that patient with a bleeding ulcer. Not saying he's a bad doctor but his personality was such where he went with the flow. I definitely could see him worrying more about money and success over the virus. I remember when Dr. Drew initially downplayed the virus like it wasn't a big deal. He had egg on his face in the end and even admitted as much. I could see Jake just like Dr. Drew and getting burned.
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I could maybe see Hannah having a breakdown over the fact that she dodged certain death by not having Huntington's only to have to deal with this now.
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^ That's a great thought!