According to Fran Kranz (love him), it's not just you if you think you see something happening between him and Dr. Claire Saunders (Amy Acker).
We actually asked about his feelings for fellow lab rat Ivy (Liza Lapira), and he turned his answer into a statement about Dr. S! According to Fran,
"Ivy and Topher are buddies. I think one other question is Dr. Saunders and Topher. I wouldn't count on anything romantic coming near Topher for
a long time, but there's an interesting relationship with Dr. Saunders."

E!Online

Shippers;
Alexa
Guinevere
Talkative One
**SuperGirl**
only dreaming
In Fair Verona
Emmaliza
Kiane
DefineDelicate
I_Wish_I_Was_Kerry
techno babble
tatablp
no limits
natih_faith
Enisy
laliXD
TVWeirdo07
Pagan Angel
DiagonalZipper

Honorary Shipper
Fran Kranz

Reasons;
Because there's serious sexual tension there!
Because they've shared a few moments.
Because we love their banter.
Because they work together.
Because they speak in code.
Because they want to play doctor with each other.
Because "she has an acid wit that she usually reserves for Topher."
Because he "may only be kidding about being smitten with her (or not)."
Because he calls her 'Doc'
Because "He Likes Her"
Because Topher is the one to get Claire out of her shell!

Bios and Moments made by In Fair Verona

Videos;
You Don't Know Me

Quotes;
1x03
Dr. Claire Saunders: You sent Echo on a high-risk engagement?
Topher Brink: Doctor Saunders! How nice of you to annoy me.

1x05
Topher Brink: The actual procedure isn't any more complicated than laser eye correction, it ain't brain surgery.
Dr. Claire Saunders: Actually, it is brain surgery.
--
Dr. Claire Saunders: One good sneeze could bring on a seizure.
Topher Brink: Or even worse, a sneezure.
--
Topher Brink: He likes her. [Referring to Victor and Sierra]
Dr. Claire Saunders: Yeah.

1x06
Dr. Claire Saunders: Victor, can you tell me about Sierra?
Victor: Sierra is beautiful.
Topher Brink: There’s a lot of beautiful girls here bro, that’s pretty much the idea. [They look at each other] Beauty.

1x12
Claire: He said I didn't always want to be a doctor.
Topher: (after an awkward pause) Who could fathom the mind of a crazy person?
Claire: The one who made him crazy? Maybe?
--
Topher: Doctor Saunders?
Claire: I think you gave me more computer skills than would be required by a medical doctor.
It was very easy for me to hack your system. I'm curious.
Topher: About?
Claire: Well I guess I understand why they wouldn't want to waste an investment, and
I suppose why hire a new physician when you can just imprint the broken doll? But why
did you decide it was so important for me to hate you? I think that's strange.
Topher: You didn't open it.
Claire: No.
Topher: Aren't you curious to see who you really are?
Claire: I know who I am.

Links;
LJ Community
I Hate That I Love You: A CT Fansite
CT Fanlisting

Past Threads;
#1: Because there's some serious sexual tension there!