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Old 11-28-2004, 11:15 AM
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South Korean Scientists Claim Paralyzed Woman Walks After Stem Cell Therapy

This seems like a legitimate story and not something from a tabloid source. If it's true it's a great thing..

Quote:
Korean Scientists Succeed in Stem Cell Therapy

By Kim Tae-gyu
Staff Reporter

A team of Korean researchers claimed Thursday they had performed a miracle by enabling a patient, who could not even stand up for the last 19 years, to walk with stem cell therapy.

During a press conference, the scientists said they had last month transplanted multi-potent stem cells from umbilical cord blood to the 37-year-old female patient suffering from a spinal cord injury and she can now walk on her own.

The team was co-headed by Chosun University professor Song Chang-hun, Seoul National University professor Kang Kyung-sun and Han Hoon, Ph.D, from the Seoul Cord Blood Bank (SCB).

The stem cell transplantation was performed on Oct. 12 this year and in just three weeks she started to walk with the help of a walker, Song said.

The patient¡'s lower limbs were paralyzed after an accident in 1985 damaged her lower back and hips. Afterward she spent her life in bed or in a wheelchair.

For the unprecedented clinical test, the scientists isolated stem cells from umbilical cord blood and then injected them into the damaged part of the spinal cord.

The sensory and motor nerves of the patient started to improve 15 days after the operation and she could move her hips. After 25 days, her feet responded to stimulation.

Earlier in October 2003, Song¡'s team also staged a clinical test with stem cells originating from umbilical cord blood by injecting them into another patient's spine.

"Back then we injected stem cells into spinal fluid and failed to get a good result. This time around, we directly targeted the spine and the method made a difference," Song said.

Song¡'s team look to further test efficiency of the new therapy with four more patients as soon as they get the green light from Chosun University ethics board and the government.

Song¡'s team plan to report their research to the scientific world within the first half of next year.

Immeasurable Upside Potential

Professor Kang and Han, Song¡'s colleagues who co-led the research, noted the new therapy has a huge upside potential when applied to real treatments, without arousing ethical disputes.

Seoul National University professor Hwang Woo-suk surprised the world last February by announcing his groundbreaking exploit of cloning a human embryo and taking stem cells from it.

The technology is expected to lead to breakthrough treatments for many hard-to-cure diseases, for instance, by creating replacement organs and tissues.

At the same time, however, the feat also fueled an ethical debate that spans science, politics and religion, especially regarding the possibility of reproductive human cloning.

In comparison, Kang said stem cells originating from the blood of umbilical cords would not raise such problems since that blood is routinely discarded after the birth of a baby.

"There have been many controversial debates on embryonic stem cells and also such stem cells are not practical due to their property of possibly causing teratoma (cancer of cells)" he explained.

Kang added that since cord blood stem cells are later than embryonic stem cells, they have little chance of causing the fatal teratoma.

"Embryonic stem cells are omni-potent in that they can divide into any thing even including a tumor cell. But cord blood stem cells are developed enough not to cause such troubles while retaining as powerful a differentiation capacity at the same time," he claimed.

Another upside of cord blood stem cells is that they can adapt to the injected bodies without triggering a big negative inner reaction, which are common in other transplantations, according to Han, Ph.D, of the SCB.

"We don't need a strict match between cord blood stem cell type and the immune system of a patient because the latter accepts the former pretty well thanks to its immaturity" Han said.

In other transplantation operations, just a slight mismatch based on the human leukocyte antigen test would cause a catastrophic result due to immune system's resistance.

The SCB currently retains blood from about 45,000 umbilical cords and they are enough to cover all Koreans, amply demonstrating the immeasurable potential of the new therapy.

voc200@koreatimes.co.kr
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Old 11-28-2004, 01:52 PM
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Thanks for posting this ceilirose. This would really be a miracle if it's legitimate. I hope that it is.
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Old 11-28-2004, 02:04 PM
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The people who voted for George Bush shouldn't receive the benefits or stem cell research.

If you're against stem cell research then you should also reject the benefits of stem cell research!

Governor Schwarzanegger and the residents of California deserve a big hand for voting to fund stem cell research in that state.
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Old 12-16-2004, 06:36 PM
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bump
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Old 12-16-2004, 06:56 PM
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Milt, you George Bush isn't against umblilcal cord cell research, only embryotic, which has already been proven to do more dammage than good. So beofre you get all high and mighty about how those who voted for him shouldn't get the benefits, you might want to find out more about it, more than some articla that none of us are sure is real, and more importantly, you might want to spend a day with somebady who has a spinal cord injury and voted against embryotic stem cell research.
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Old 12-16-2004, 07:03 PM
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Why wouldn't that article be real? Do you have proof that it's not?

Also can you provide a link which talks about why embyonic stem cell research has done more harm than good?
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Old 12-16-2004, 07:10 PM
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"There have been many controversial debates on embryonic stem cells and also such stem cells are not practical due to their property of possibly causing teratoma (cancer of cells)" he explained.

Did you miss that part?
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Old 12-16-2004, 07:15 PM
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Originally posted by 86amanda86
"There have been many controversial debates on embryonic stem cells and also such stem cells are not practical due to their property of possibly causing teratoma (cancer of cells)" he explained.

Did you miss that part?
No...did you miss the word possibly in that sentence. The last time I looked there was a difference in the meaning of possibly vs definitely. Not to mention a proven link.

Do you take any medications? Have you ever looked at the fine print that comes with a prescription? Every medication out there can produce a serious side effect in the right circumstance. Does that mean we should stop taking antibiotics because it will cause stomach problems? I don't think so..stem cell research still is in it's infancy. It has the potential to offer great breakthroughs in many diseases. We'll never know what it can produce unless we try.
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Old 12-16-2004, 07:22 PM
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stomach problems and cancer are very different hun. When we are talking about life and death, "possible" is a big word.
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Old 12-16-2004, 07:31 PM
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stomach problems and cancer are very different hun. When we are talking about life and death, "possible" is a big word.
The 'hun' is condescending..I'm somebody's 'hun' but not yours, ok?

You still haven't given any proof of all the damage that embryonic stem call could produce other than quote a scientists's theory about possible side effects. If you don't want to be hopeful about new breakthroughs then that's your deal.

I nursed my dad through the end stages of Parkinson's disease. Having seen someone deteriorate because of that disease I think that any research that shows promise should be supported. There are no givens but I'd rather have hope than just give up and accept it as some Divine will. Worse..not even try because there could be serious side effects. The drugs that currently help Parkinson's patients have some serious side effects and believe me..it's not pleasant to see.
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Old 12-16-2004, 07:36 PM
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Sounds to good to be true but I hope it is. I think "W" is crazy to be against stem cell research.
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Old 12-16-2004, 07:38 PM
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I am very hopeful, there is no hope that my brother will ever walk again. But you have no idea how much hope I have that there will come a way that other families don't have to got through the pain that comes with these things. Trust me, I have seen almost every article and every study on embyonic research and the evidence just isn't there. I'm equally certain that one day there will be a way to cure these things, but I hate to see other people get their hopes up about embryonic stem cell research when it just doesn't seem to be adding up.
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Old 12-16-2004, 07:48 PM
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Originally posted by 86amanda86
I am very hopeful, there is no hope that my brother will ever walk again. But you have no idea how much hope I have that there will come a way that other families don't have to got through the pain that comes with these things. Trust me, I have seen almost every article and every study on embyonic research and the evidence just isn't there. I'm equally certain that one day there will be a way to cure these things, but I hate to see other people get their hopes up about embryonic stem cell research when it just doesn't seem to be adding up.
Where are all these articles you talk about which say that the evidence isn't there?

Everything I've read goes on the premise that it's a hopeful avenue for research but there are no proven cures yet. For instance research at Harvard has shown that they can take human cells from an embryo and coax them to form retinal cells. That's a potential breakthrough that could help with blindness and other eye diseases. Should we just stop all that now become some think a definitive cure might never be found? You don't know unless you try.
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Old 12-16-2004, 11:29 PM
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No all Im saying is that I think there will be better ways to get the same results if we keep looking.
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Old 12-17-2004, 03:53 AM
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...yay south korea?

and that person [the reporter] has the same surname as i do.

well, my korean name.

then again, it is the majority of the korean population.
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