Punky Brewster is an American sitcom about a girl named Punky Brewster (Soleil Moon Frye) being raised by her foster parent (George Gaynes). The show ran on NBC from September 16, 1984 to March 9, 1986, and again in first-run syndication from October 30, 1987 to May 27, 1988.

Punky Brewster spawned an animated spin-off It's Punky Brewster. The series featured the original cast voicing their respective characters. The cartoon was produced by Ruby-Spears, and aired on NBC from September 14, 1985 to December 6, 1986.

Penelope "Punky" Brewster (Soleil Moon Frye) is a warm, funny and bright child. Her father walked out on her family, then her mother abandoned her at a Chicago shopping center, leaving Punky alone with her dog Brandon. Afterwards, Punky discovered a vacant apartment in a local building.

The building is managed by photographer Henry Warnimont (George Gaynes), an elderly widower who is something of a grouch. Punky quickly became friends with Cherie Johnson (played by Cherie Johnson, the niece of series creator David W. Duclon), a young girl who lived upstairs in Henry's building with her grandmother, Betty Johnson (Susie Garrett), who worked as an RN at the local Cook County Hospital. Henry discovers Punky in the empty apartment across from his, and hears her story.

The relationship between the two blossoms, despite red tape from social workers (who ultimately rally to Henry's side). As their day in court approaches, the state forces Punky to stay at Fenster Hall, a shelter for orphaned and abandoned children, which makes her realize how close she has grown to Henry. Finally, their day arrives, and the court approves Henry to become Punky's foster dad. Later on, Henry legally adopts her.

Punky's other friends are geeky Allen Anderson (Casey Ellison) and stuck-up rich girl Margaux Kramer (Ami Foster). During the NBC run, Punky's teachers were regularly seen; in the first season, cheerful Mrs. Morton (Dody Goodman) and in the second season, hip Mike Fulton (T.K. Carter). Mike formed a close relationship with Punky and her friends, and was also portrayed as a social crusader of sorts.