I remember seeing that interview on youtube last year but for some reason I can't find it on youtube anymore...maybe it got deleted?
But I did find this different interview with Francois, but it was to promote season 2 not S3:
at 1:18 he mentioned Cesare's relationship with Lucrezia will deepen in S2, and he seemed rather shy and giggled when the interviewer asked him "what do you mean by deeper?"
it's the same reaction he had during that interview for S3 and Holly's reaction